The moment Dr No - and in a sense, spy movies as a genre - shifts tectonically is when Bond and Honey Ryder, captured on Crab Key, post-decontamination and drugging, are shuffled into the eponymous villain’s dining room.
Generally speaking, Bond villains are far more obsessed with power and projects than they are with sex. And none is more sexless than Auric Goldfinger, the eponymous villain of the third Bond instalment. The ridiculousness of his Fort Knox plan is in inverse proportion to his level of interest in base physical desires.